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Myasthenia gravis (sometimes abbreviated MG; from the Greek myastheneia, lit. 'condition of no strength in the muscle', and Latin gravis, 'serious') is a neuromuscular disease leading to fluctuating muscle weakness and fatiguability. At 20 cases per 100,000 (in the U.S.),[1] it is one of the lesser known autoimmune disorders. Weakness is typically caused by circulating antibodies that block acetylcholine receptors at the post-synaptic neuromuscular junction,[2] inhibiting the stimulative effect of the neurotransmitter acetylcholine. Myasthenia is treated with immunosuppressants, cholinesterase inhibitors and, in selected cases, thymectomy.